Pitx2 confers left morphological, molecular, and functional identity to the sinus venosus myocardium
نویسندگان
چکیده
منابع مشابه
Pitx2 confers left morphological, molecular, and functional identity to the sinus venosus myocardium
AIMS The sinus venous myocardium, comprising the sinoatrial node (SAN) and sinus horns (SH), is a region subject to congenital malformations and cardiac arrhythmias. It differentiates from symmetric bilateral mesenchymal precursors, but morphological, molecular, and functional left/right differences are progressively established through development. The role of the laterality gene Pitx2 in this...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2011
ISSN: 1755-3245,0008-6363
DOI: 10.1093/cvr/cvr314